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KMID : 1102220230420010004
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Kidney Research and Clinical Practice
2023 Volume.42 No. 1 p.4 ~ p.26
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Cinnamon: an aromatic condiment applicable to chronic kidney disease
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Lais de Souza Gouveia Moreira
Isabela de Souza da Costa Brum
Drielly C. M. de Vargas Reis
Liana Trugilho
Tuany R. Chermut
Marta Esgalhado
Ludmila F. M. F. Cardozo
Peter Stenvinkel
Paul G. Shiels
Denise Mafra
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Abstract
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Cinnamon, a member of the Lauraceae family, has been widely used as a spice and traditional herbal medicine for centuries and hasshown beneficial effects in cardiovascular disease, obesity, and diabetes. However, its effectiveness as a therapeutic intervention forchronic kidney disease (CKD) remains unproven. The bioactive compounds within cinnamon, such as cinnamaldehyde, cinnamicacid, and cinnamate, can mitigate oxidative stress, inflammation, hyperglycemia, gut dysbiosis, and dyslipidemia, which are commoncomplications in patients with CKD. In this narrative review, we assess the mechanisms by which cinnamon may alleviate complicationsobserved in CKD and the possible role of this spice as an additional nutritional strategy for this patient group.
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KEYWORD
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Chronic renal insufficiency, Cinnamomum zeylanicum, Inflammation, Oxidative stress, Spices
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